Not known Factual Statements About phenobarbital sodium drug class
Not known Factual Statements About phenobarbital sodium drug class
Blog Article
pentobarbital decreases levels of toremifene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers maximize amount of toremifene metabolism, lowering the constant-point out concentration in serum.
pentobarbital will decrease the extent or effect of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Keep an eye on Closely (one)pentobarbital will lower the extent or effect of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. CYP3A4 inducers haven't been researched, coadministration not recommended by company
pentobarbital will lower the level or effect of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to your lower in fentanyl plasma concentrations, lack of efficacy or, probably, improvement of a withdrawal syndrome inside of a patient who's got developed Actual physical dependence to fentanyl.
DOSAGE AND ADMINISTRATION Dosages of barbiturates should be individualized with full understanding of their particular properties and proposed rate of administration.
pentobarbital will minimize the extent or effect of bedaquiline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Avoid coadministration of bedaquiline with powerful CYP3A4 inducers as a result of prospective for lowered therapeutic effect
pentobarbital will lessen the level or effect of fentanyl intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration sodium pentobarbital anesthesia mice of fentanyl with CYP3A4 inducers could lead on to the lessen in fentanyl plasma concentrations, deficiency of efficacy or, possibly, development of the withdrawal syndrome inside a client who has formulated physical dependence to fentanyl.
pentobarbital will minimize the extent or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Mysterious.
pentobarbital will minimize the extent or effect of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will reduce the extent or effect of estrogens conjugated artificial by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or effect of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
The effect with the resultant decreased blood levels of griseofulvin on therapeutic reaction has not been set up. Nonetheless, it would be preferable to avoid concomitant administration of those drugs.
pentobarbital will lower the extent or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Potent or moderate CYP3A4 inducers may well boost level of diazepam elimination; as a result, efficacy of diazepam might be diminished.
pentobarbital will decrease the extent or effect of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.